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Abstract #4732

Direct Comparison of Integrated PET-MRI and PET-CT FDG Quantification in the Dementia Population

Timothy Shepherd 1 , Bang-Bin Chen 2 , Kent Friedman 1 , Christopher Glielmi 3 , Thomas Koesters 1 , Kimberly Jackson 1 , Yu-Shin Ding 1 , David Faul 3 , and Fernando Boada 1

1 Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 2 Department of Medical Imaging, National Taiwan University Hospital, Taiwan, 3 Siemens Healthcare, New York, NY, United States

Research indicates combining PET and MRI biomarkers of Alzheimer's disease will provide better stratification of patients with suspected dementia for clinical diagnosis and monitoring of experimental therapies. Integrated PET-MRI is ideally positioned to provide this information simultaneously, but PET-MRI radiotracer quantification is not trivial and its accuracy not established. We report direct comparison of MRI- to CT-based attenuation correction methods in the same patients with suspected dementia.

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