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Abstract #4748

Quantitative Carotid MR/PET Imaging: Comparisons to PET/CT and clinical evaluation of MR-Attenuation Correction versus CT-Attenuation Correction in MR/PET Emission Data

Jason Bini 1,2 , Philip M Robson 1 , Claudia Calcagno 1 , Mootaz Eldib 1 , and Zahi A Fayad 1

1 Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States, 2 Department of Biomedical Engineering, The City College of New York, New York, New York, United States

18F-Fluorodeoxyglocuse (FDG) positron emission tomography (PET) has shown promise in quantifying metabolic activity of inflammation in atherosclerotic plaques in patients. In this study, we examine the quantitative differences between our carotid artery imaging protocol on a PET/CT and an MR/PET scanner, controlling for circulation time. Large differences between PET/CT and MR/PET were observed. When reconstructing the same PET data with MR- and CT-based attenuation maps in the MR/PET reconstruction we see a high quantitative correlation between reconstructed PET images. This study supports the use of MR/PET for quantitative measure of metabolic activity in the carotid arteries.

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