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Abstract #4807

High Resolution Rodent Cochlea Imaging on a 3T Clinical Magnet

Joshua D Kaggie 1,2 , K Craig Goodrich 1 , Seong-Eun Kim 1 , Michael J Beck 1 , Dennis L Parker 1,2 , Robb Merrill 1 , Travis A Abele 3 , Richard Wiggins 3 , and J Rock Hadley 1

1 Utah Center for Advanced Imaging Research, Radiology, University of Utah, Salt Lake City, UT, United States, 2 Physics, University of Utah, Salt Lake City, UT, United States, 3 Neuroradiology, University of Utah, Salt Lake City, UT, United States

This work developed a small animal system that could acquire good in vivo 100μm isotropic resolution images of a guinea pig cochlea on a 3T clinical MR system. The system used improved gradients, RF coils, and animal holder/monitoring equipment when compared to a standard clinical magnet. FLASH imaging was used to assess the quality of the system. Gadolinium increased the SNR and contrast of the cochlea during FLASH imaging. The small animal system obtained good 100μm isotropic resolution images of the cochlear chambers in a scan time of only 33 minutes.

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