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Abstract #4924

Quantitative comparison of localized in vivo hepatic 31 P MRS at 7T.

Marek Chmelik 1 , Michal Povazan 1 , Martin Krk 1,2 , Stephan Gruber 1 , Ladislav Valkovic 1 , Siegfried Trattnig 1 , and Wolfgang Bogner 1

1 High Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, Austria, 2 Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Austria

The feasibility of commonly used 31 P-MRS localization techniques (1D-ISIS, 3D-ISIS, 2D CSI and 3D CSI; n=9) that are suitable for both localized MRS of focal lesions and semi-localized MRS for use in diffuse pathologies in the human liver was demonstrated at 7T. Liver 31 P MRS at 7T provides improved data quality in acceptable measurement time. All methods provided data with high spectral quality regarding signal to noise, small linewidth and low CRLB(<11%). Voxel volume and acquisition time corrected SNR was similar for all the methods.

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