Abstract #0024
In vivo measurement of vessel wall diffusion anisotropy in carotid arteries
Peter Opriessnig 1 , Harald Mangge 1 , Rudolf Stollberger 2 , David Porter 3 , Hannes Deutschmann 4 , and Gernot Reishofer 5
1
Clinical Institute for Medical and Chemical
Laboratory Diagnosis, Medical University of Graz, Graz,
Austria,
2
Institute
of Medical Engineering, Graz University of Technology,
Austria,
3
MR
R&D, Siemens AG, Healthcare Sector, Erlangen, Germany,
4
Department
of Radiology, Division of Vascular and Interventional
Radiology, Medical University of Graz, Austria,
5
Department
of Radiology, Division of Neuroradiology, Medical
University of Graz, Austria
Multi-contrast MRI has become a well-recognized tool to
study the complexity of an atherosclerotic plaque in
order to predict lesion vulnerability. Diffusion tensor
imaging (DTI) could be an additional measure that
provides information on the influence of plaque
components on the diffusion process, which may help to
understand the formation of a complex disease. In this
work, we demonstrate the feasibility to investigate the
orientation of diffusion anisotropy in healthy human
carotids in vivo. Tangential and radial diffusion were
measured by the combination of a read-out segmented EPI
(rs-EPI) with a 2D special gradient direction scheme.
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