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Abstract #0032

Free-Breathing Pediatric MRI with Nonrigid Motion Correction and Acceleration

Joseph Yitan Cheng 1,2 , Tao Zhang 1,2 , Nichanan Ruangwattanapaisarn 3 , Marcus T. Alley 2 , Martin Uecker 4 , John M. Pauly 1 , Michael Lustig 4 , and Shreyas S. Vasanawala 2

1 Electrical Engineering, Stanford University, Stanford, CA, United States, 2 Radiology, Stanford University, Stanford, CA, United States, 3 Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 4 Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, United States

The goal of this work is to develop and assess motion correction techniques for free-breathing pediatric MRI. First, a variable-density sampling and radial-like phase-encode ordering scheme was developed for a 3D Cartesian acquisition. Second, intrinsic multichannel butterfly navigators were used to measure respiratory motion. Lastly, these estimates were applied for both motion-weighted data-consistency in an accelerated imaging reconstruction, and for nonrigid motion correction using a localized autofocusing framework. With IRB approval and informed consent, 22 pediatric patients were imaged, and representative features were evaluated. With the proposed methods, diagnosable high-resolution abdominal volumetric scans can be obtained from free-breathing acquisitions that are comparable to longer respiratory-gated scans.

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