Abstract #0041
Hybrid MR/US-guided HIFU for abdominal targets: in vivo demonstration of 3D motion correction and focal point locking on an absolute reference marker
Lorena Petrusca 1 , Gibran Manasseh 2 , Zarko Celicanin 3 , Romain Breguet 4 , Oliver Bieri 3 , Vincent Auboiroux 5 , Christoph D Becker 4 , Sylvain Terraz 4 , and Rares V. Salomir 6
1
University of Geneva, Geneva, Geneva,
Switzerland,
2
Radiology,
University Hospitals of Geneva, Geneva, Switzerland,
3
University
Hospital Basel, Basel, Switzerland,
4
University
Hospitals of Geneva, Geneva, Switzerland,
5
LETI
CEA, Grenoble, France, France,
6
Radiology,
University Hospitals of Geneva, Geneva, Geneva,
Switzerland
Treatments using high-intensity focused ultrasound
(HIFU) in the abdominal region remain challenging due to
respiratory organ motion. Various methods have been
attempted in the past to achieve motion-compensated HIFU
therapy, using ultrasound (US) imaging, magnetic
resonance imaging (MRI), or both simultaneously. Here, a
truly hybrid US-MRI guided HIFU (US-MRgHIFU) method was
used to plan and control the treatment in vivo. 3D
prospective motion correction was implemented at a frame
rate of 15Hz on pig liver and kidney. An absolute target
was used to demonstrate the spatial accuracy of the
method, which was found to be in the sub-millimeter
range.
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