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Abstract #0055

Hybrid Encoding for Quantitative Electron Paramagnetic Resonance Imaging

Hyungseok Jang 1,2 , Chandramouli Gadisetti 3 , Devasahayam Nallathamby 4 , Murali C Krishna 4 , and Alan B McMillan 1

1 Radiology, University of Wisconsin, Madison, WI, United States, 2 Electrical and Computer Engineering, University of Wisconsin, Madison, WI, United States, 3 GenEpria Consulting Inc., Columbia, MD, United States, 4 Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States

In EPR oxygen imaging, spatial and temporal resolution is challenged due to low spin densities and short relaxation times. Therefore, it is crucial to achieve accelerated imaging to allow greater flexibility in resolving spatial and temporal oxygen variations. In this study, we successfully employed a hybrid encoding scheme that greatly reduces encoding time compared with conventional SPI encoding techniques utilized in EPRI. Moreover, this new technique allows the reconstruction of images across multiple echo times from a single acquisition to enable quantification of oxygen via T 2 * mapping.

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