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Abstract #0148

In vivo multifrequency MR elastography for the assessment of portal hypertension before and after transjugular intrahepatic portosystemic shunt (TIPS) implantation

Jing Guo 1 , Christian Althoff 2 , Carsten Bning 3 , Eckart Schott 4 , Thomas Krncke 5 , Jrgen Braun 6 , and Ingolf Sack 2

1 Radiology, Charit - Universittsmedizin Berlin, Berlin, Berlin, Germany, 2 Radiology, Charit - Universittsmedizin Berlin, Berlin, Germany, 3 Krankenhaus Waldfriede,Akademisches Lehrkrankenhaus der Charit, Berlin, Germany, 4 Department of Hepatology and Gastroenterology, Charit - Universittsmedizin Berlin, Berlin, Germany, 5 Clinic for Diagnostic Radiology and Neuroradiology, Klinikum Augsburg, Bavaria, Germany, 6 Department of Medical Informatics, Charit - Universittsmedizin Berlin, Berlin, Germany

High-resolution multifrequency MRE based on MDEV inversion was applied to patients with portal hypertension before and after TIPS placement. The magnitude shear moduli | G * |of liver and spleen were both sensitive to the portal decompression following TIPS. The observed linear correlation between spleen viscoelasticity and HVPG raises the prospect of an image-based and noninvasive assessment of portal pressure by MR elastography in the follow-up of TIPS placements.

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