Abstract #0181
Dual Agent Relaxivity Cancellation (DARC) Imaging, a Novel Imaging Method for Dark Blood Post-Contrast Imaging: Application to MR Lymphangiography
Jeffrey H Maki 1 , Noah Briller 1 , Peter C Neligan 2 , and Gregory J Wilson 1
1
Radiology, University of Washington,
Seattle, WA, United States,
2
Plastic
Surgery, University of Washington, Seattle, WA, United
States
A novel MR imaging method using two contrast agents (one
for enhancement of non-blood-pool tissues, and one for
suppression of blood-pool signal), named Dual Agent
Relaxivity Cancellation (DARC), was developed for the
visualization of lymphatic channels. The MR
lymphangiography technique utilizes the T1 signal
enhancement of intracutaneously injected gadobenate and
the blood-pool T2* signal suppression of intravenously
injected ferumoxytol. When imaged with mDixon using
relatively long TEs (4-8ms), lymphatic channels are
easily visualized without venous overlay.
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