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Abstract #0190

Real-time Automatic Resolution Adaption (AURA) for dynamic contrast-enhanced MRI

Ina Nora Kompan 1,2 , Benjamin Richard Knowles 3 , and Matthias Guenther 1,2

1 Fraunhofer MEVIS, Bremen, Bremen, Germany, 2 mediri GmbH, Heidelberg, Baden-Wrttemberg, Germany, 3 Universittsklinikum Freiburg, Freiburg, Baden-Wrttemberg, Germany

Pharmacokinetic modeling is used in dynamic contrast-enhanced MRI to quantify tissue physiology. High temporal and spatial resolutions are both needed, but are not compatible. In this work, a resolution adaption sequence is presented which in real-time adapts temporal resolutions to the measured contrast-enhanced signal changes. The sequence is validated using a perfusion phantom and is compared to an only low spatial and only high spatial resolution sequence. For the phantom, the adaptive sequence provides comparable fitting accuracy to the low temporal resolution sequence and high spatial resolution images at the signal peak.

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