Real-time Automatic Resolution Adaption (AURA) for dynamic contrast-enhanced MRI
Ina Nora Kompan 1,2 , Benjamin Richard Knowles 3 , and Matthias Guenther 1,2
Fraunhofer MEVIS, Bremen, Bremen, Germany,
GmbH, Heidelberg, Baden-Wrttemberg, Germany,
Freiburg, Freiburg, Baden-Wrttemberg, Germany
Pharmacokinetic modeling is used in dynamic
contrast-enhanced MRI to quantify tissue physiology.
High temporal and spatial resolutions are both needed,
but are not compatible. In this work, a resolution
adaption sequence is presented which in real-time adapts
temporal resolutions to the measured contrast-enhanced
signal changes. The sequence is validated using a
perfusion phantom and is compared to an only low spatial
and only high spatial resolution sequence. For the
phantom, the adaptive sequence provides comparable
fitting accuracy to the low temporal resolution sequence
and high spatial resolution images at the signal peak.
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