Accelerating Magnetic Resonance Fingerprinting using t-Blipped Simultaneous Multi-Slice Acquisition

Magnetic resonance fingerprinting (MRF) permits non-invasive quantification of multiple important properties simultaneously. In conventional MRF, an acquisition time of approximately 10s is required for each imaging slice. In this work, we developed a new simultaneous multi-slice (SMS) technique to speed up MRF acquisition. Specifically, we proposed t-blipped SMS-MRF method, which utilizes additional Gz blip encodings to provide phase modulation between the signals of simultaneously acquired slices and creates controlled-aliasing in the temporal axis. We demonstrated the ability of t-blipped SMS-MRF technique to accelerate MRF acquisition by 2-fold (MB=2) and provide good parameter mapping at an acquisition time of 5s per slice using both simulation and in vivo acquisition. We find that the t-blipped SMS technique can speed up the MRF acquisition allowing a rapid quantitative parameter mapping in a clinically relevant time frame.

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