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Abstract #0247

Accelerating Magnetic Resonance Fingerprinting using t-Blipped Simultaneous Multi-Slice Acquisition

Huihui Ye 1,2 , Dan Ma 3 , Yun Jiang 3 , Stephen F Cauley 1 , Yiping Du 2 , Lawrence L Wald 1 , Mark A Griswold 3 , and Kawin Setsompop 1

1 MGH/HST Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 2 Zhejaing University, Hangzhou, Zhangjiang, China, 3 Case Western Reserve University, Ohio, United States

Magnetic resonance fingerprinting (MRF) permits non-invasive quantification of multiple important properties simultaneously. In conventional MRF, an acquisition time of approximately 10s is required for each imaging slice. In this work, we developed a new simultaneous multi-slice (SMS) technique to speed up MRF acquisition. Specifically, we proposed t-blipped SMS-MRF method, which utilizes additional Gz blip encodings to provide phase modulation between the signals of simultaneously acquired slices and creates controlled-aliasing in the temporal axis. We demonstrated the ability of t-blipped SMS-MRF technique to accelerate MRF acquisition by 2-fold (MB=2) and provide good parameter mapping at an acquisition time of 5s per slice using both simulation and in vivo acquisition. We find that the t-blipped SMS technique can speed up the MRF acquisition allowing a rapid quantitative parameter mapping in a clinically relevant time frame.

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