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Abstract #0333

Simultaneous frequency and T2 mapping, applied to thermometry and to susceptibility-weighted imaging

Cheng-Chieh Cheng 1 , Chang-Sheng Mei 2 , Pelin Aksit Ciris 3,4 , Robert V. Mulkern 4,5 , Mukund Balasubramanian 4,5 , Hsiao-Wen Chung 1 , Tzu-Cheng Chao 6 , Lawrence P. Panych 3,4 , and Bruno Madore 3,4

1 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 2 Department of Physics, Soochow University, Taipei, Taiwan, 3 Department of Radiology, Brigham and Women's Hospital, Boston, MA, United States, 4 Harvard Medical School, Boston, MA, United States, 5 Department of Radiology, Boston Children's Hospital, Boston, MA, United States, 6 Department of Computer Science and Information Engineering, National Cheng-Kung University, Tainan, Taiwan

Both T2 mapping and field mapping can provide rich clinically-relevant information. During thermal therapies for example, field maps provide temperature information through the proton resonance frequency effect while T2 can reveal tissue damage and edema. In brain imaging, field maps reveal iron deposits and bleeding through susceptibility effects while T2 enables tumor detection and segmentation. Typically, pulse sequences based on spin echoes are needed for T2 mapping while gradient echoes are needed for field mapping, making it difficult to simultaneously acquire both types of information. A dual-pathway multi-echo pulse sequence is employed here to generate both T2 and field maps from the same acquired data.

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