Abstract #0333
Simultaneous frequency and T2 mapping, applied to thermometry and to susceptibility-weighted imaging
Cheng-Chieh Cheng 1 , Chang-Sheng Mei 2 , Pelin Aksit Ciris 3,4 , Robert V. Mulkern 4,5 , Mukund Balasubramanian 4,5 , Hsiao-Wen Chung 1 , Tzu-Cheng Chao 6 , Lawrence P. Panych 3,4 , and Bruno Madore 3,4
1
Graduate Institute of Biomedical Electronics
and Bioinformatics, National Taiwan University, Taipei,
Taiwan,
2
Department
of Physics, Soochow University, Taipei, Taiwan,
3
Department
of Radiology, Brigham and Women's Hospital, Boston, MA,
United States,
4
Harvard
Medical School, Boston, MA, United States,
5
Department
of Radiology, Boston Children's Hospital, Boston, MA,
United States,
6
Department
of Computer Science and Information Engineering,
National Cheng-Kung University, Tainan, Taiwan
Both T2 mapping and field mapping can provide rich
clinically-relevant information. During thermal
therapies for example, field maps provide temperature
information through the proton resonance frequency
effect while T2 can reveal tissue damage and edema. In
brain imaging, field maps reveal iron deposits and
bleeding through susceptibility effects while T2 enables
tumor detection and segmentation. Typically, pulse
sequences based on spin echoes are needed for T2 mapping
while gradient echoes are needed for field mapping,
making it difficult to simultaneously acquire both types
of information. A dual-pathway multi-echo pulse sequence
is employed here to generate both T2 and field maps from
the same acquired data.
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