Abstract #0341
Navigated PSF Mapping for Distortion-Free High-Resolution In-Vivo Diffusion Imaging at 7T
Myung-Ho In 1 , Posnansky Oleg 1 , and Oliver Speck 1
1
Biomedical Magnetic Resonance,
Otto-von-Guericke University, Magdeburg, Germany
For high-resolution diffusion-weighted imaging, which is
used for microstructural characterization of human brain
in research as well as clinical applications,
single-shot echo-planar imaging may be not suitable due
to severe T2 blurring and susceptibility- and
eddy-current-induced geometric distortions, especially
at ultra-high field. Several multi-shot approaches have
been proposed to mitigate such effects. In this study, a
point-spread function based diffusion-weighted imaging
approach is newly proposed. In contrast to multi-shot
approaches, this method doesnt suffer any T2 blurring
and geometric distortions and enables a clear and
detailed delineation of human brain structures in-vivo.
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