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Abstract #0392

Magnetic Resonance Elastography of Liver: Utility in Autoimmune Hepatitis

Jin Wang 1,2 , Meng Yin 1 , Sudhakar Kundapur Venkatesh 1 , and Richard L. Ehman 1

1 Radiology, Mayo Clinic, Rochester, MN, United States, 2 Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China

Autoimmune hepatitis (AIH) is a chronic liver disease of unknown etiology with a tendency to relapse and progress to cirrhosis. We assessed the diagnostic accuracy of 2D-MRE in predicting cirrhosis in biopsy-proven AIH with no prior treatment and in patients with AIH who already received treatment. Study results showed that MRE has excellent accuracy in detecting cirrhosis in AIH in both pretreatment and treatment groups. Preliminary study also showed that MRE is useful to assess treatment response in patients on treatment. MRE, therefore is a useful non-invasive technique for detection of cirrhosis in AIH and assessment of treatment response.

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