Abstract #0394
Comparing in vivo and ex vivo imaging in an Alzheimers mouse model using tensor-based morphometry
Holly Elizabeth Holmes 1 , Nicholas Powell 1,2 , Jack Wells 1 , Niall Colgan 1 , Ozama Ismail 1 , James O'Callaghan 1 , Da Ma 1,2 , Michael J O'Neill 3 , Emily Catherine Collins 4 , Manuel Jorge Cardoso 2 , Marc Modat 2 , Elizabeth Fisher 5 , Sebastian Ourselin 2 , and Mark F Lythgoe 6
1
Centre for Advanced Biomedical Imaging,
University College London, London, Greater London,
United Kingdom,
2
Centre
for Medical Image Computing, University College London,
London, Greater London, United Kingdom,
3
Eli
Lilly & Co. Ltd, Windlesham, Surrey, United Kingdom,
4
Eli
Lilly & Company, Indianapolis, United States,
5
Department
of Neurodegenerative Diseases, University College
London, London, Greater London, United Kingdom,
6
University
College London, London, Greater London, United Kingdom
The tradeoffs when imaging mouse models of
neurodegenerative disease using in vivo and ex vivo MRI
have been explored using the rTg4510 mouse model of
Alzheimer's disease
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