Abstract #0439
Simultaneous Quantitative Mapping of T 1 , T 2 *, and Magnetic Susceptibility with Multi-Echo MP2RAGE at 7 T
Riccardo Metere 1 , Harald E. Mller 1 , Gunnar Krger 2,3 , Tobias Kober 2,3 , and Andreas Schfer 1
1
Max Planck Institute for Human Cognitive and
Brain Sciences, Leipzig, Germany,
2
Siemens
ACIT CHUV Radiology, Siemens Healthcare IM BM PI &
Department of Radiology CHUV, Lausanne, Switzerland,
3
LTS5,
cole Polytechnique Fdrale de Lausanne, Lausanne,
Switzerland
Knowledge of the relaxation times is essential for
understanding the biophysical mechanisms underlying
image contrast, and can be related to tissue
composition. Quantitative experiments are essential for
cross-study comparisons, but often require longer
acquisition times. Using the prototype Multi-Echo (ME)
MP2RAGE pulse sequence, we show the possibility of
obtaining reliable T
1
, T
2
*, and
magnetic susceptibility maps that are inherently
co-registered. The acquisition time required for such
experiments is comparable to the time required for T
1
map
acquisition with MP2RAGE. This result is obtained as a
trade-off between resolution and the parameters of the
multi-echo readouts.
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