Abstract #0450
Reproducibility of Phase-Contrast MRI in the Coronary Artery: Towards Noninvasive Pressure Gradient Measurement and Quantification of Fractional Flow Reserve
Zixin Deng 1,2 , Yang Qi 2 , Xiaoming Bi 3 , Zhaoyang Fan 2 , and Debiao Li 1,2
1
Bioengineering, University of California,
Los Angeles, Los Angeles, California, United States,
2
Biomedical
Imaging Research Institute (BIRI), Cedars-Sinai Medical
Center, Los Angeles, California, United States,
3
R&D,
Siemens Healthcare, Los Angeles, California, United
States
Fractional Flow Reserve (FFR) invasively evaluates the
functional severity of an intermediate stenosis by
measuring the stenotic pressure drop via
catheterization. Noninvasive pressure measurements using
PC-MRI and Navier-Stokes equations have been shown in
the aorta, carotid and renal arteries. In this study,
the feasibility and reproducibility of PC-MRI and
noninvasive pressure calculations were evaluated in the
coronary arteries to establish the robustness of
noninvasive FFR measurement using MRI. Excellent
correlations were observed in the through-plane and
slightly lower in the in-plane velocities between the
repeated acquisitions. The noninvasive pressure values
in healthy subjects were near zero, as expected.
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