Meeting Banner
Abstract #0452

Aortic stiffness, cardiac energetic, systolic and diastolic function in healthy ageing.

Jehill D Parikh 1 , Kieren G Hollingsworth 1 , Andrew M Blamire 1 , and Guy MacGowan 2

1 Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, Tyne and Wear, United Kingdom, 2 Cardiology, Freeman Hospital, Newcastle Upon Tyne, Tyne and Wear, United Kingdom

Aorta rapidly expands during a ventricular contraction accommodating the majority (50% or more) of the stroke volume. Aortic stiffness increases with age, and is regarded as an independent risk factor in the development of cardiovascular disease. Additionally, normal ageing is characterized by age-related diastolic dysfunction, altered systolic strains and impaired myocardial energetics. In this study we explore associations between age-related increase in aortic stiffness and cardiac energetics and left ventricular function. Such associations may provide important insights into how normal ageing affects the heart, which may allow development of potential treatments to attenuate this process.

This abstract and the presentation materials are available to members only; a login is required.

Join Here