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Abstract #0456

Longitudinal Monitoring of Hepatic Blood Flow in patients with portal hypertension before and after TIPS implantation with 4D Flow MRI

Peter Bannas 1,2 , Alejandro Roldn-Alzate 1 , Kevin M Johnson 3 , Michael A Woods 1 , Utaroh Motosugi 1 , Oliver Wieben 3 , Scott B Reeder 1,3 , and Harald Kramer 1,4

1 Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2 Radiology, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany, 3 Medical Physics, University of Wisconsin-Madison, WI, United States, 4 Radiology, Ludwig-Maximilians-University Hospital, Munich, Bavaria, Germany

Transjugular intrahepatic portosystemic shunt (TIPS) is non-surgical method of portal decompression to treat major complications of portal hypertension. Currently, the combination of Doppler ultrasound and invasive portosystemic pressure measurements are applied to monitor patients before and after TIPS placement. An alternative operator-independent and non-invasive technique would be highly desirable. In this study we demonstrate the feasibility of 4D-flow MRI for qualitative and quantitative analyses of hepatic blood flow before and then 2 and 12 weeks after TIPS placement. 4D flow MRI is feasible for longitudinal hemodynamic monitoring of the blood flow in the portal vein and the TIPS stent.

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