Abstract #0514
Effect of Repetitive Transcranial Magnetic Stimulation on fMRI Resting-State Connectivity in Multiple System Atrophy
Ying-hui Chou 1 , Hui You 2 , Han Wang 2 , Yan-Ping Zhao 2 , Bo Hou 2 , Nan-kuei Chen 1 , and Feng Feng 2
1
Duke Brain Imaging and Analysis Center,
Durham, NC, United States,
2
Peking
Union Medical College Hospital, Beijing, China
In this study, we demonstrated that 10-session 5-Hz
repetitive transcranial magnetic stimulation (rTMS)
targeting at the left primary motor area could be used
to improve motor function in patients with Multiple
System Atrophy (MSA). The improvement of motor function
was accompanied by increases in resting-state functional
connectivity associated with the default mode network.
Our findings shed light on the clinical utility of the
rTMS technique, and the identification of rTMS- and
symptoms-related functional networks may generate new
insights into future therapeutic candidate for patients
with MSA.
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