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Abstract #0552

High resolution three dimensional imaging of extracranial and intracranial arteries

Lei Zhang 1 , Yongjun Tao 2 , Xiaoqing Hu 1 , Jun Wu 2 , Xin Liu 1 , and Yiu-Cho Chung 1

1 Paul C. Lauterbur Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academic of Sciences, Shenzhen, Guangdong, China, 2 Neurology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China

This study proposes the use of a neurovascular coil with an appropriately optimized T1w-SPACE for vessel wall imaging of intracranial and extracranial arteries in one scan. The sequence combined good blood suppression (through DANTE) and improved T1 contrast (through a flip-down pulse) to improve image quality. An optimized refocusing pulses flip angle series for T1w-SPACE and a good neurovascular coil increased the SNR needed for high spatial resolution. The method covers a volume of 212mm x 159mm x 40mm with an isotropic spatial resolution of 0.6mm in 7.5min. The patient study showed that the method would be clinically relevant.

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