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Abstract #0554

Intraplaque Hemorrhage Detection and Threshold Selection for Simultaneous Noncontrast Angiography and IntraPlaque Hemorrhage (SNAP) Images

Jin Liu 1 , Marina S. Ferguson 1 , Jinnan Wang 2 , Daniel S. Hippe 1 , Niranjan Balu 1 , William S. Kerwin 1 , Thomas S. Hatsukami 1 , and Chun Yuan 1

1 University of Washington, Seattle, WA, United States, 2 Philips Research North America, NY, United States

Intraplaque hemorrhage (IPH), an important destabilizing factor in atherosclerosis progression, can be identified as hyperintensity region in Simultaneous Noncontrast Angiography and intraPlaque hemorrhage (SNAP) images. In this study, validation of SNAP in detecting IPH with histology was performed, demonstrating that SNAP can identify carotid IPH accurately in vivo. Furthermore, a threshold of 740 based on the original intensity of SNAP images were obtained by optimization, in order to detect carotid IPH automatically.

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