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Abstract #0557

Time-efficient whole-heart coronary plaque characterization with simultaneously acquired MRA

Yibin Xie 1,2 , Young Jin Kim 3 , Jianing Pang 1 , Jung-Sun Kim 4 , Qi Yang 1 , Zhaoyang Fan 1 , Hyuk-Jae Chang 4 , and Debiao Li 1

1 Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States, 2 University of California, Los Angeles, Los Angeles, California, United States, 3 Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, 4 Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea

Recently T1-weighted MRI with or without contrast enhancement has been used for characterizing coronary plaques showing promising prognostic value for coronary events. However the drawbacks of current protocols using conventional Cartesian acquisition and respiratory gating may hinder the clinical application of this technique due to limited anatomical coverage, low anisotropic resolution and the requirement of a separate bright-blood MRA scan. We developed a time-efficient protocol based on 3DPR with simultaneously acquired MRA to address these limitations and performed preliminary clinical validation on 11 CAD patients using CT angio, X-ray angio, and intracoronary OCT as reference.

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