Accurate Multi-resolution Discrete Search Method to Estimate the Number and Directions of Axon Packs from DWMRI

We propose a Multi-resolution Discrete Search method to estimate white matter microstructure based on three key ideas: 1) A Multi-resolution Discrete Search to determine the Principal Diffusion Directions; 2) The parameter-free determination of the number of axon bundles using the Bayesian Information Criterion and 3) A Simultaneous Denoising and Fitting procedure to achieve robustness with respect to noise.

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