Abstract #0594
Relationships between excitation-inhibition balance and whole-brain oxygen extraction fraction in human brain
Swati Rane 1 , Brandon Ally 2 , Emily Mason 2 , Subechhya Pradhan 3 , Erin Hussey 2 , Kevin Waddell 3 , Hanzhang Lu 4,5 , and Manus Donahue 2,3
1
Radiology and Radiological Sciences,
Vanderbilt University Institute of Imaging Science,
Nashville, TN, United States,
2
Neurology,
Vanderbilt University, Nashville, TN, United States,
3
Radiology
and Radiological Sciences, Vanderbilt University,
Nashville, TN, United States,
4
Radiology,
UT Southwestern, Dallas, TX, United States,
5
Psychiatry,
UT Southwestern, Dallas, TX, United States
We investigated the relation between brain
neurotransmitter concentrations, venous oxygen
saturation, and oxygen extraction fraction. We show that
venous oxygen saturation is inversely proportional to
the ratio of GABA/Glx.
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