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Abstract #0754

Whole Brain Pulsed Arterial Spin Labelling at Ultra High Field with a B1 + -optimised Adiabatic Labelling Pulse

Kieran O'Brien 1,2 , Fabian Zimmer 2 , Steffen Bollmann 2 , Josef Pfeuffer 3 , Keith Heberlein 4 , and Markus Barth 2

1 Healthcare Sector, Siemens Ltd, Brisbane, Australia, 2 The Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, 3 Siemens Healthcare, Erlangen, Germany, 4 Siemens Healthcare, Boston, MA, United States

Pulsed Arterial Spin Labelling (ASL) techniques should benefit from the increased signal to noise ratio available at ultra high field. Previous proof-of-concept ASL studies have been limited to the superior regions of the brain due to poor labelling efficiency of the blood in the neck. We propose and show that through replacing the frequency offset corrected inversion (FOCI) adiabatic pulse with a low-B1 power time resampled (TR-)FOCI pulse we can obtain reliable perfusion signal at 7T across the whole brain without the need for dielectric pads or dedicated labelling coils.

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