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Abstract #0807

Prospective Comparison of a Contrast-Enhanced MRI Protocol with Contrast-Enhanced MDCT for the Primary Diagnosis of Acute Appendicitis in the General Population

Michael D Repplinger 1,2 , Perry J Pickhardt 2 , Douglas R Kitchin 2 , Jessica B Robbins 2 , Timothy J Ziemlewicz 2 , and Scott B Reeder 2,3

1 Emergency Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, 2 Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, 3 Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States

The aim of our study was to determine the test characteristics of an MRI protocol consisting of unenhanced, contrast-enhanced, and DWI to diagnose appendicitis. This was a prospective study including patients ≥12 years for whom a CT was ordered to evaluate for appendicitis. We enrolled 165 patients; all images were interpreted by three radiologists. Sensitivity and specificity (95% CI) were 95.7% (84.7-99.5%) and 88.8% (81.4-93.6%) for unenhanced MRI with DWI, 95.7% (84.5-99.5%) and 88.1% (80.2-93.2%) for CE-MRI, and 97.9% (88.1-100%) and 92.7% (85.9-96.4%) for CE-MDCT. We conclude that this MRI protocol was as accurate as CE-MDCT to diagnose appendicitis.

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