Abstract #0864
Pushing X-ray CT out of the equation: In vivo RASOR MRI-based seed detection for post-implant dosimetry in LDR prostate
Peter Roland Seevinck 1 , Cornelis A van den Berg 2 , Frank Zijlstra 1 , Marielle E Philippens 2 , Stan Jelle Hoogcarspel 2 , Jan J Lagendijk 2 , Maximus A Viergever 1 , and Marinus Adriaan Moerland 2
1
Image Sciences Institute, University Medical
Center Utrecht, Utrecht, Netherlands,
2
Department
of Radiotherapy, University Medical Center Utrecht,
Netherlands
This study demonstrates the feasibility of in vivo
MRI-based localisation of implanted brachytherapy seeds
with positive contrast and high specificity, using a
robust, clinically available imaging sequence with RASOR
reconstruction and straightforward post-processing. This
approach may enable MRI-only postimplant dosimetry,
preventing the need for CT-based seed detection and
image fusion and all related disadvantages, including
radiation exposure, registration errors and additional
costs. Interestingly, the optimized RASOR sequence
facilitates visualisation of bone structures. As a
consequence other applications of the proposed technique
may be bone and fiducial imaging for MRI-based treatment
planning in external beam radiotherapy and attenuation
correction in PET-MRI.
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