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Abstract #0867

Integration of Active MR Tracking into Adaptive Radiation Therapy Treatment Planning

Wei Wang 1,2 , Akila N Viswanathan 2 , Antonio L Damato 2 , Zion T Tse 3 , Yue Chen 3 , Ravi T Seethamraju 4 , Clare M Tempany 1 , Robert A Cormack 2 , and Ehud J Schmidt 1

1 Radiology, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, United States, 2 Radiation Oncology, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, United States, 3 The University of Georgia, GA, United States, 4 MR R&D, Siemens Healthcare, MA, United States

In interstitial brachytherapy, catheters are normally inserted into the tumor under MRI guidance. Due to the inaccuracy of MRI catheter visualization, CT is required after placement to localize catheters for treatment planning. We propose an adaptive radiation treatment planning process based entirely on MRI, using catheter trajectories generated by an active MR-tracking system specifically developed for fast and accurate localization of metallic catheters. This provides intra-operative dosimetric feedback to clinicians during catheter implantation, which allows for adaptive repositioning or addition of catheters. It will improve tumor coverage, reduce toxicity to normal tissues and potentially eliminate the need for subsequent CT.

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