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Abstract #0878

Carotid Atherosclerotic Plaque Surface Condition Evaluation Utilizing Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (SNAP) Sequence

Shuo Chen 1 , Xihai Zhao 1 , Niranjan Balu 2 , Haining Liu 2 , Zechen Zhou 1 , Jinnan Wang 2,3 , Rui Li 1 , Chun Yuan 1,2 , and Huijun Chen 1

1 Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, Beijing, China, 2 Department of radiology, University of Washington, Seattle, United States, 3 Philips Research North America, Briarcliff Manor, NY, United States

In carotid atherosclerotic plaque, surface conditions such as juxtaluminal calcification (JCA) and ulceration are believed to be linked to plaque vulnerability. Conventionally, multi-contrast sequences (T1w-TSE, T2w-TSE, 3D TOF) are used to determine the plaque components and vulnerability. However, conventional multi-contrast is constrained by limited longitudinal coverage, long acquisition time and inter-scan motion. Recently, a simultaneous non-contrast angiography and intraplaque hemorrhage (SNAP) sequence was proposed for carotid artery imaging. In this work, we sought to evaluate the feasibility of carotid plaque surface condition evaluation using SNAP sequence alone.

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