Abstract #0886
Relative Enhanced Diffusivity (RED) as a Marker of Breast Tumor Microvasculature
Jose R. Teruel 1,2 , Pl E. Goa 3,4 , Torill E. Sjbakk 1 , Agnes stlie 4 , Hans E. Fjsne 5,6 , and Tone F. Bathen 1
1
Circulation and Medical Imaging, Norwegian
University of Science and Technology, Trondheim, Norway,
2
St.Olavs
Hospital, Trondheim, Norway,
3
Physics,
Norwegian University of Science and Technology,
Trondheim, Norway,
4
Radiology,
St.Olavs Hospital, Trondheim, Norway,
5
Cancer
Research and Molecular Medicine, Norwegian University of
Science and Technology, Trondheim, Norway,
6
Surgery,
St.Olavs Hospital, Trondheim, Norway
In this study, we have explored the feasibility of
obtaining a diffusion weighted imaging derived parameter
sensitive to blood microcirculation employing only two
non-zero b-values. This new parameter, relative enhanced
diffusivity (RED), presented a high correlation with the
initial area under the curve parameter derived from
dynamic contrast enhanced MRI kinetic curve, and
improved lesion differentiation compared with the
standard apparent diffusion coefficient.
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