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Abstract #0918

A parallel transmit spectral-spatial pulse design method for ultra-high field MRS combining LSQR and optimal control based optimization

Tingting Shao 1 , Yun Zhang 2 , Nikolai Avdievich 1 , Steffen Glaser 2 , and Anke Henning 1,3

1 Max Planck Institute for Biological Cybernetics, Tbingen, Baden-Wrttemberg, Germany, 2 Department of Chemistry, Technical University of Munich, Garching, Germany, 3 Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland

This work presents a new spectral-spatial (SPSP) parallel transmit pulse design method for 1H MRS applications in ultra-high field MRI. Based on the recently developed parallel transmission technology, the pulse is first designed by using a subspace preconditioned LSQR method in purpose of locating a global minimum, and is afterwards optimized by using a quasi-Newton based optimal control (OC) method to find a local minimum answer. By combining these two algorithms in this way, SPSP pulses that offer increased robustness against B1+ inhomogeneity and minimized chemical shift displacement artifacts can be achieved and therefore adopted in MRS applications.

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