Abstract #0922
Rapid Multi-Orientation Susceptibility Mapping with Wave-CAIPI
Berkin Bilgic 1 , Luke Xie 2 , Russell Dibb 2 , Christian Langkammer 1 , Aysegul Mutluay 1 , Huihui Ye 1 , Jonathan R Polimeni 1 , Chunlei Liu 2 , Lawrence L Wald 1 , and Kawin Setsompop 1
1
Martinos Center for Biomedical Imaging,
Charlestown, MA, United States,
2
Radiology,
Duke University Medical Center, Durham, NC, United
States
Rapid 3D-GRE imaging with Wave-CAIPI attains high
quality reconstruction at 15-fold acceleration to
facilitate fast acquisition of extremely time consuming
COSMOS and STI protocols at multiple head orientations.
This technique revealed exquisite cortical contrast and
detailed depiction of iron rich nuclei; it enabled
detection of anisotropic structures such as white matter
tracts. Wave-CAIPI permits a 5:35 min acquisition per
orientation at 0.5 mm isotropic resolution for COSMOS,
and a 90 sec acquisition per orientation at 1.1 mm
isotropic resolution for STI. Furthermore, we deployed a
novel EPI-FLEET sequence for rapid and low-distortion
calibration acquisition, thus enabling coil sensitivity
estimation of both head and body coils from a 10 sec
scan.
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