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Abstract #0958

Single-Spin Echo Multiband Diffusion Imaging with Slice Select Gradient Reversal

Matthew J. Middione 1 , Hua Wu 2 , Robert F. Dougherty 2 , Kangrong Zhu 3 , Adam B. Kerr 3 , and John M. Pauly 3

1 Applied Sciences Laboratory West, GE Healthcare, Meno Park, CA, United States, 2 CNI, Stanford University, Stanford, CA, United States, 3 Electrical Engineering, Stanford University, Stanford, CA, United States

Echo planar imaging (EPI), especially single shot EPI, is the method of choice for diffusion MRI (dMRI) due to its short scan time and motion insensitivity. However, it is sensitive to chemical-shift artifacts due to the low bandwidth in the phase-encoding direction, which requires the use of efficient fat suppression. Herein we analyze the effects of removing chemical shift artifacts with different fat saturation and suppression techniques for single-spin-echo, dual-spin-echo, and multiband imaging. We propose a single-spin-echo dMRI sequence using multiband imaging and slice select gradient reversal to provide efficient fat suppression, comparable SNR, and reduced scan time.

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