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Abstract #0966

Connectivity-based atlas of human brain white matter in ICBM-152 space.

Anna Varentsova 1 , Shengwei Zhang 2 , Ekaterina Shanina 1 , and Konstantinos Arfanakis 2,3

1 Physics Department, Illinois Institute of Technology, Chicago, IL, United States, 2 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States, 3 Rush Alzheimer's Disease Center, Rush University, Chicago, IL, United States

Digital human brain atlases consisting of MRI-based templates and semantic labels delineating different brain regions serve a critical role in neuroimaging, mainly facilitating spatial normalization and automated segmentation, for the purposes of voxel-wise, region-of-interest, and network analyses. As part of the IIT Human Brain Atlas project (www.nitrc.org/projects/iit2), we have recently developed, anatomical as well as state-of-the-art diffusion tensor and high angular resolution diffusion imaging (HARDI) templates, as well as probabilistic gray matter (GM) labels in ICBM-152 space. The purpose of this project was to construct the first probabilistic connectivity-based atlas of human brain white matter (WM) in ICBM-152 space.

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