In vivo high resolution imaging of the mouse neurovasculature

A method allowing in vivo magnetic resonance imaging of the mouse neurovasculature at high resolution (<100 m) is presented. It uses the Resovist contrast agent and a dedicated head coil. Images and extracted vessel sizes obtained in vivo are compared against ex vivo results obtained at the same resolution. A study of the vessels size distributions in three main regions of the brain is presented and used as a basis for the comparison.

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