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Abstract #0980

Detection of Pulmonary Nodules by Ultra-short TE Sequences in Oncology Patients using a PET/MR System

Nicholas Scott Burris 1 , Peder Larson 1 , Kevin M Johnson 2 , Michael D Hope 3 , Spencer Behr 3 , and Thomas A Hope 3

1 Radiology, University of California San Francisco, San Francisco, CA, United States, 2 University of WisconsinMadison, WI, United States, 3 University of California San Francisco, CA, United States

Using an investigational 3T PET/MR system, 3D ultra-short TE (UTE) and zero TE sequences (ZTE) were used to evaluate pulmonary nodules in 5 oncology patients undergoing clinical PET/CT, with CT considered the gold-standard. UTE was highly sensitive for nodules ≥8mm (95%) and moderately sensitive for smaller nodules between 4-6mm in size (71%). ZTE was less sensitive for >8mm (51%) and nodules 4-6mm (42%). PET-avid nodules were detected at higher rates by both sequences. Preliminary results of UTE for pulmonary nodule detection are promising, and UTE may offer an alterative approach to PET/MR evaluation of oncology patients in the future.

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