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Abstract #1011

Isotropic 3-D CINE Imaging with Sub-2mm Resolution in a Single Breath-Hold

Jens Wetzl 1,2 , Michaela Schmidt 3 , Michael O. Zenge 3 , Felix Lugauer 1 , Laszlo Lazar 4 , Mariappan Nadar 5 , Andreas Maier 1,2 , Joachim Hornegger 1,2 , and Christoph Forman 3

1 Pattern Recognition Lab, Department of Computer Science, Friedrich-Alexander-Universitt Erlangen-Nrnberg, Erlangen, Germany, 2 Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universitt Erlangen-Nrnberg, Erlangen, Germany, 3 Siemens AG, Healthcare, Imaging & Therapy Systems, Magnetic Resonance, Erlangen, Germany, 4 Siemens SRL, Corporate Technology, Brasov, Romania, 5 Siemens Corporation, Corporate Technology, Princeton, NJ, United States

MR CINE acquisitions represent the gold standard for the assessment of left ventricular function. Although recently introduced single breath-hold real-time 2-D CINE and 3-D CINE acquisitions feature a high in-plane resolution, small details could be missed by the low spatial resolution in slice direction. To address this limitation, a single breath-hold 3-D CINE acquisition is proposed in this work featuring an isotropic resolution below 2 mm. In-vivo experiments were performed on 5 healthy volunteers and cardiac function was compared to gold standard 2-D CINE.

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