Abstract #1025
Joint estimation of microstructural and biomechanical features of the brain using a phase sensitive reconstruction of DWIs
Tim Sprenger 1,2 , Jonathan I. Sperl 2 , Axel Haase 1 , Brice Fernandez 3 , Christopher Hardy 4 , Luca Marinelli 4 , Michael Czisch 5 , Philipp Saemann 5 , and Marion I. Menzel 2
1
IMETUM, Technical University, Munich,
Germany,
2
GE
Global Research, Munich, Germany,
3
GE
Healthcare, Munich, Germany,
4
GE
Global Research, Niskayuna, NY, United States,
5
Max
Planck Institute of Psychiatry, Munich, Select, Germany
Diffusion weighted magnetic resonance imaging (DWI)
allows for non-invasive measurement of microstructural
features of the human brain. Usually all data processing
in DWI is based on the magnitude of the complex MR
signal, and the inherent phase of the signal is
discarded as it is considered to be spoiled by different
sources. One source for a non-zero phase in DWI signal
is the pulsation of the brain itself, which is
potentially impacted by disorders such as hydrocephalus
or traumatic brain injury. In this work, a phase
correction approach is introduced to sequentially remove
all phase contributions except for brain pulsation.
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