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Abstract #1027

Time to move on: an FOD-based DEC map to replace DTI's trademark DEC FA

Thijs Dhollander 1 , Robert Elton Smith 1 , Jacques-Donald Tournier 2,3 , Ben Jeurissen 4 , and Alan Connelly 1,5

1 The Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia, 2 Centre for the Developing Brain, King's College London, London, United Kingdom, 3 Department of Biomedical Engineering, King's College London, London, United Kingdom, 4 iMinds-Vision Lab, University of Antwerp, Antwerp, Belgium, 5 The Florey Department of Neuroscience, University of Melbourne, Melbourne, Victoria, Australia

The "traditional" directionally-encoded colour (DEC) FA map is an icon of DTI, but is also affected by its inherent flaws. The first eigenvector is known to be ill-defined in regions of crossing fibres, resulting in misleading specific DEC values as well as "false edges" in the overall map. Additionally, the FA shows naturally low values in these regions. In a clinical setting, this might potentially lead to false positive findings; but also to false negative ones in case these false features mask out or otherwise distract from real pathological features. We propose an FOD-based DEC map that solves these issues.

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