Abstract #1151
Comparison of prostate tumor volume delineation between multi-parametric MRI sequences when planning for hypofractionated radiotherapy
Hugh Harvey 1 , Veronica Morgan 2 , David Dearnaley 3 , Sharon Giles 2 , Alison Macdonald 2 , Julia Murray 3 , and Nandita deSouza 1
1
CRUK Cancer Imaging Centre, The Institute of
Cancer Research, Sutton, Surrey, United Kingdom,
2
The
Royal Marsden NHS Foundation Trust, Surrey, United
Kingdom,
3
Radiotherapy
& Imaging, The Institute of Cancer Research, London,
United Kingdom
Delineation of the tumor region-of interest is crucial
when planning boost doses of radiation therapy to a
dominant intraprostatic tumor nodule. Comparison of
prostatic tumor volume measurements defined on T2W
images, Apparent Diffusion Coefficient maps and Dynamic
Contrast Enhanced images in 16 patients due for
radiation dose-boosting to tumor revealed a significant
difference in measured volumes between the sequences,
with T2W-derived volumes being up to 48.7% larger than
DCE-derived volumes and therefore most useful in the
context of radiation therapy planning.
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