Meeting Banner
Abstract #1164

Using Multiparametric MRI to Differentiate Prostate Cancer in the Anterior Aspect of the Gland

Olga Starobinets 1,2 , Jeffry Simko 3,4 , Kyle Kuchinsky 3 , Sonam Machingal 1 , John Kurhanewicz 1,2 , Peter R Carroll 4 , Kirsten L Greene 4 , and Susan M Noworolski 1,2

1 Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 2 Graduate Group in Bioengineering, UC Berkeley, Berkeley, CA, United States, 3 Pathology, UCSF, San Francisco, CA, United States, 4 Urology, UCSF, San Francisco, CA, United States

The purpose of this study was to use semi-quantitative parameters derived from dynamic contrast-enhanced (DCE) MRI, 1hydrogen-MR spectroscopic imaging (MRSI), diffusion MR and MRI to differentiate benign and malignant, as well as high-risk from low-risk prostate cancers in the anterior aspect of the prostate using whole-mount pathology as the standard of reference. A logistic regression combination of parameters provided ROC AUC=0.983 for discriminating benign from malignant tissues and AUC=0.824 for distinguishing between low-risk and high-risk cancer.

This abstract and the presentation materials are available to members only; a login is required.

Join Here