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Abstract #1181

Cartilage evaluation by gagCEST at 3 Tesla after arthroscopic partial meniscectomy

Olgica Zaric 1 , Pavol Szomolanyi 1 , Vladimir Mlynarik 1 , Vladimir Juras 1 , and Siegfried Trattnig 1

1 High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

Recent studies has shown that removal of the entire meniscus can lead to the development of osteoarthritis in a high proportion of cases in a long run. This study used 3 Tesla gagCEST MRI for early postoperative quantitative evaluation of biochemical changes in articular cartilage adjacent to operated meniscus after PMA. We observed lower gagCEST values in cartilage adjacent to the operated meniscus than in the healthy cartilage within the same subject. This loss in GAG content could be biomarker of early cartilage degeneration. gagCEST at 3 Tesla has great potential in the investigation of early signs of osteoarthritis.

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