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Abstract #1201

High resolution T1ρ-mapping of articular cartilage in the wrist at 3T

Joep van Oorschot 1 , Mark Gosselink 1 , Fredy Visser 2 , Alexandra de Rotte 1 , Peter Luijten 1 , and Dennis Klomp 1

1 University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Philips Healthcare, Best, Noord-Brabant, Netherlands

T1ρ-mapping is a promising quantitative technique to detect cartilage damage at an early stage, at which tissue damage might be reversible. Here we test the feasibility of high resolution T1ρ-mapping mapping of articular cartilage at 3T. T1ρ-mapping was performed using a T1ρ-prepared 3D FFE sequence. 4 images with different spin-lock (SL) preparation times with an amplitude of 500 Hz were acquired (SL = 1,12,24,48 ms). The T1ρ-relaxation time in the articular cartilage in healthy subjects was 572 ms. High resolution T1ρ-mapping of the wrist at 3T is feasible, and a promising technique to assess early cartilage damage in the wrist.

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