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Abstract #1203

T1rho mapping of the entire femoral cartilage using novel depth and angle dependent analysis

Taiki Nozaki 1 , Yasuhito Kaneko 1 , Hon J. Yu 1 , Kayleigh Kaneshiro 1 , Ran Schwarzkopf 2 , Takeshi Hara 3 , and Hiroshi Yoshioka 1

1 Radiological Sciences, University of California, Irvine, Orange, California, United States, 2 Orthopaedic Surgery, University of California, Irvine, Orange, California, United States, 3 Intelligent Image Information, Gifu University Graduate School of Medicine, Gifu, Japan

T1rho-weighted MR imaging enables us to detect early cartilage degeneration in early osteoarthritis patients before appearing morphological change. However for the methodology of segmentation, the number of slices measured is only one or several slices, not all slices from the knee in most of reports, and there is no previous publication about normal entire femoral T1rho map profiles for analyzing regional or cartilage layer variations. The objective of this study was to create normalized T1rho profiles of healthy entire femoral cartilage with 3 dimensional angular and depth dependent analysis, and evaluate their usefulness.

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