T1 measurements in the intervertebral discs: Analysis of reproducibility and diurnal changes
Volkan Emre Arpinar 1 , Weitian Chen 2 , and L Tugan Muftuler 1,3
Department of Neurosurgery, Medical College
of Wisconsin, Milwaukee, Wisconsin, United States,
Applied Science Laboratory, GE Healthcare, California,
for Imaging Research, Medical College of Wisconsin,
Milwaukee, WI, United States
It was shown that MRI T1Rho images could be used to
assess proteoglycan loss; therefore, it can be employed
as a quantitative measure of intervertebral discs (IVD)
degeneration, especially in early stages. In order to
use T1Rho as a diagnostic or prognostic tool, however,
one needs to assess the reproducibility of these
measurements. Moreover, earlier studies showed diurnal
changes in the IVDs during rest and loading conditions.
Therefore the goal of this work was to assess the
reproducibility and diurnal changes in T1Rho
measurements in the IVDs.
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