Skeletal Muscle Perfusion Measured with Pseudo-Continuous Arterial Spin-Labeling MRI After Dorsiflexion Contractions

In this study we tested the feasibility of pseudo-continuous arterial spin labeling (pCASL) MRI to measure changes in skeletal muscle perfusion following a short high-intensity dorsiflexion exercise protocol. PCASL detected increases in perfusion of the primary dorsiflexors (tibialis anterior and extensor digitorum longus) after the contractions, and the perfusion values were shown to have good day-to-day reproducibility. This study shows the feasibility of applying pCASL to measure skeletal muscle perfusion after isometric fatiguing dorsiflexion contractions in healthy adults.

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