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Abstract #1244

Myogenic Differentiation of Magnetically Labeled Mesenchymal Stem Cells

Natalie M. Pizzimenti 1 , Christiane Mallett 2 , Robert W. Wiseman 1,2 , and Erik M. Shapiro 2

1 Physiology Department, Michigan State University, East Lansing, MI, United States, 2 Radiology Department, Michigan State University, East Lansing, MI, United States

The purpose of this study was to investigate the ability of MSCs to differentiate into myogenic cells with varying magnetic labeling conditions. MSCs show morphological changes toward the myogenic lineage after 6 weeks in muscle media even with the introduction of magnetic particles. This is a new tool that will allow MRI-based cell tracking to further our understanding in skeletal muscle repair.

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