Meeting Banner
Abstract #1263

Diffusion-weighted thermometry using subarachnoid space cerebrospinal fluid in subacute carbon monoxide poisoning patients

Shunrou Fujiwara 1 , Yoshichika Yoshioka 2 , Tsuyoshi Matsuda 3 , Hideaki Nishimoto 1 , Toshiyuki Murakami 1 , Akira Ogawa 1 , Kuniaki Ogasawara 1 , Makoto Sasaki 4 , and Takaaki Beppu 1,5

1 Department of Neurosurgery, Iwate Medical University, Morioka, Iwate, Japan, 2 WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan, 3 MR Applications and Workflow Asia Pacific, GE Healthcare Japan, Tokyo, Japan, 4 Division of Ultrahigh Field MRI, Institu, Iwate Medical University, Yahaba, Iwate, Japan, 5 Hyperbaric Medicine, Iwate Medical University, Morioka, Iwate, Japan

We investigate the potential of cerebrospinal fluid (CSF) based DWI-thermometry measured in the subarachnoid space, where the CSF flow quietly changes comparing with the lateral ventricle, to estimate brain temperature (BT) in subacute carbon monoxide (CO) poisoned patients who show the strong imbalance between perfusion and metabolism in the brain. Our results suggested that the higher BT measured in the subarachnoid space by DWI than that measured in white matter by MRS might substantially reflect the brain metabolism in the subacute CO-poisoned patients because the CSF in the subarachnoid space directly lies on the cortex.

This abstract and the presentation materials are available to members only; a login is required.

Join Here